Cr1l ELISA Kit for Mouse(Mus musculus) | EIAab.comCr1l ELISA Kit for Mouse(Mus musculus)

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Cr1l (Gene name),

Complement component receptor 1-like protein (Protein name ), CR1L_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cr1l(Crry;Cry);

Protein name:

Complement component receptor 1-like protein;

Alternative:

Protein p65;Complement regulatory protein Crry;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with C3b.

Function:

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

483

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

483:

KEDSCVRLQS | LLTSQENSST | TSPARNSLTQ | EVS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:12946

UniGene:

Mm.301652

SMR:

Q64735

Pfam:

PF00084

Uniprot:

Q64735

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ELISA Kit for Mouse Complement component receptor 1-like protein

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E15277h

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96T

ELISA Kit for Mouse Complement component receptor 1-like protein

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E15277m

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96T

ELISA Kit for Mouse Complement component receptor 1-like protein

Cat.:

E15277r

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96T

CLIA Kit for Mouse Complement component receptor 1-like protein

Cat.:

U15277m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Complement component receptor 1-like protein

Cat.:

U15277h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Complement component receptor 1-like protein

Cat.:

U15277r

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MSDS:

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96T

Polyclonal Antibody for Mouse Complement component receptor 1-like protein

Cat.:

P15277Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Complement component receptor 1-like protein

Cat.:

P15277Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Complement component receptor 1-like protein

Cat.:

P15277Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Complement component receptor 1-like protein

Protein for Mouse Complement component receptor 1-like protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The murine complement receptor gene family: III. The genomic and transcriptional complexity of the Crry and Crry-ps genes."
Paul M.S. , Aegerter-Shaw M. , Cepek K. , Miller M.D. , Weis J.H.
J. Immunol.144:1988-1996(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORMS 1 AND 2)
strain: BALB/c.
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 64-437 (ISOFORM 1)
strain: C57BL/6J.
tissue: Pancreas.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: Czech II.
tissue: Mammary gland.
5.

"The murine complement receptor gene family analysis of mCRY gene products and their homology to human CR1."
Paul M.S. , Aegerter-Shaw M. , O'Brien S.E. , Kurtz C.B. , Weis J.H.
J. Immunol.142:582-589(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-477 (ISOFORM 2);NUCLEOTIDE SEQUENCE [MRNA] OF 12-167 (ISOFORM 1);TISSUE SPECIFICITY
tissue: Liver.
tissue: Spleen.
6.

"Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1."
Molina H. , Wong W. , Kinoshita T. , Brenner C. , Foley S. , Holers V.M.
J. Exp. Med.175:121-129(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF."
Li B. , Sallee C. , Dehoff M. , Foley S. , Molina H. , Holers V.M.
J. Immunol.151:4295-4305(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein."
Kim Y.-U. , Kinoshita T. , Molina H. , Hourcade D. , Seya T. , Wagner L.M. , Holers V.M.
J. Exp. Med.181:151-159(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells."
Fernandez-Centeno E. , de Ojeda G. , Rojo J.M. , Portoles P.
J. Immunol.164:4533-4542(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"A critical role for murine complement regulator crry in fetomaternal tolerance."
Xu C. , Mao D. , Holers V.M. , Palanca B. , Cheng A.M. , Molina H.
Science287:498-501(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE
11.

"Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack."
Miwa T. , Zhou L. , Hilliard B. , Molina H. , Song W.-C.
Blood99:3707-3716(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
13.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-460; THR-463 AND SER-477;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy."
Aslam M. , Guthridge J.M. , Hack B.K. , Quigg R.J. , Holers V.M. , Perkins S.J.
J. Mol. Biol.329:525-550(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 84-401

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